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CYP3A4 inducers may raise the formation in the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Intently monitor people having ifosfamide with CYP3A4 inducers for toxicities and consider dose adjustment.pentobarbital will minimize the level or influence of midazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Ca

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